Saturday, 2 June 2012

Should You Be Taking Heart Medications?

When I tell high-risk patients that I think they should take a statin drug and explain why it will help to improve their cholesterol levels, they usually agree. But it is not unusual to get some resistance from patients who aren't well informed about the potential benefits or side effects of these drugs.


The following are some typical patient reactions:
"No! I don't want to take any medications. I want to lower my cholesterol naturally, without drugs and their side effects. Won't drugs fry my liver?"
"Sign me up! I'd rather take a pill than worry about my diet or bother with exercise!"
In both cases, these patients are just cheating themselves.
 
Patients who reject medications because they think they're not "natural" are missing out on some of the best tools in aggressive prevention. Statin drugs alone can slash the risk of having a heart attack by more than 30 percent — and by much more than that when taken in combination with other drugs such as niacin, aspirin, and/or certain blood pressure medications.

I am quick to remind patients who make remarks about drugs not being "natural" that there is nothing "natural" about having a sick artery that is burdened with plaque. I also tell them that statin drugs can actually help to restore the artery to its youthful, flexible state — the way that nature intended it to be. And I remind them that a truly "natural" cholesterol level is in the low 100s. At least that is the level found in populations with unprocessed, non-Western diets.

Patients who think that popping a pill renders diet and exercise unnecessary are also making a deadly mistake. Drugs are meant to work together with these lifestyle changes; they are not meant to replace them. Even if a combination of drugs can reduce your risk of having a heart attack by 50 percent, half of all people taking these drugs who were destined for a heart attack will still have one. That's why making lifestyle changes is so essential to further reduce risk.

Although I am a passionate believer in the power of diet and exercise, given what we know today about the effectiveness of statins and other drugs, it makes no sense at all for at-risk patients not to take them. I made this point recently when I was lecturing at a major medical center about the benefits of good fats, good carbs, and lean protein to a group of physicians. At the end of my talk, after having built a strong case for the role of diet in heart disease prevention, one doctor asked if I would be willing to conduct a study that tested the principles of the South Beach Diet as a sole therapy for patients with coronary artery disease. I was adamant that I would not. Using diet alone to treat heart disease would be ignoring 30 years of lifesaving medical advances.
So does that mean that statins should be universally prescribed in a manner akin to adding fluoride to drinking water to reduce tooth decay? That would be going too far. But statins have generally been underprescribed.

Despite numerous excellent studies documenting their effectiveness, millions of people who should be taking these cholesterol-lowering drugs are not. This means that millions of Americans have an unnecessarily high risk of suffering a heart attack, stroke, or sudden death.

A Word of Caution: 
 
Tell your doctor about all the medications and dietary supplements you take regularly, whether they're prescription or over-the-counter. When taken in combination with other drugs, many otherwise safe medications can interact, causing potentially dangerous side effects. Never stop taking a heart medication without consulting your doctor.

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